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Singer Lab Publications:

Supplementary Material From Lab Publications

216.  
ZBP1 recognition of β-actin zipcode induces RNA looping.

Chao JA, Patskovsky Y, Patel V, Levy M, Almo SC, Singer RH

Genes Dev 24(2):148-158 (2010 January 15)
Abstract | Link to Journal | Download Reprint (PDF)
 
215.  
Rrp17p Is a Eukaryotic Exonuclease Required for 5' End Processing of Pre-60S Ribosomal RNA.

Oeffinger M, Zenklusen D, Ferguson A, Wei KE, El Hage A, Tollervey D, Chait BT, Singer RH, Rout MP

Mol Cell 36(5):768-781 (2009 December 11)
Abstract | Link to Journal | Download Reprint (PDF)
 
214.  
A single molecule view of gene expression.

Larson DR, Singer RH, Zenklusen D

Trends Cell Biol 19(11):630-637 (2009 November)
Abstract | Link to Journal | Download Reprint (PDF)
 
213.  
Blocking β-catenin binding to the ZBP1 promoter represses ZBP1 expression, leading to increased proliferation and migration of metastatic breast-cancer cells.

Gu W, Pan F, Singer RH

J Cell Sci 122(11):1895-1905 (2009 June 1)
Abstract | Link to Journal | Download Reprint (PDF)
 
212.  
Imaging Transcription in Living Cells.
Darzacq X, Yao J, Larson DR, Causse SZ, Bosanac L, de Turris V, Ruda VM, Lionnet T, Zenklusen D, Guglielmi B, Tjian R, Singer RH
Annu Rev Biophys 38:173-196 (2009 June)
Abstract | Link to Publisher | Download Reprint (PDF)
 
211.  
A der(8)t(8;11) chromosome in the Karpas-620 myeloma cell line expresses only Cyclin D1: Yet both Cyclin D1 and MYC are repositioned in close proximity to the 3′ IGH enhancer.
Dib A, Glebov OK, Shou Y, Singer RH, Kuehl WM
DNA Repair 8(3):330-335 (2009 March 1)
Abstract | Link to Journal | Download Reprint (PDF)
 

210.

 
Butyrate and vitamin D3 induce transcriptional attenuation at the cyclin D1 locus in colonic carcinoma cells.
Maier S, Daroqui MC, Scherer S, Roepcke S, Velcich A, Shenoy SM, Singer RH, Augenlicht LH
J Cell Physiol 218(3):638-642 (2009 March)
Abstract | Link to Journal | Download Reprint (PDF)
 
209.  
Dendritic RNA Transport: Dynamic Spatio-Temporal Control of Neuronal Gene Expression.
Dictenberg JB, Singer RH
Encyclopedia of Neuroscience, ed Squire LR, 3:437-444. Elsevier (2009 January 11)
Abstract | Download Reprint (PDF) | ISBN: 978-0080446172
 
208.  
Cell Biology of mRNA Decay.
Grünwald D, Singer RH, Czaplinski K
Methods Enzymol 448(27):553-577 (2008 December 15)
Abstract | Link to Book Series | Download Reprint (PDF) | ISBN: 978-0123743787
 
207.  
RNA in Cells.
de Turris V, Singer RH
Single Molecule Dynamics in Life Science, eds Yanagida T and Ishii Yoshiharu, 171-190. Wiley-VCH (2008 December 15)
ISBN: 978-3527312887
 
206.  
Single-RNA counting reveals alternative modes of gene expression in yeast.
Zenklusen D, Larson DR, Singer RH
Nat Struct Mol Biol 15(12):1263-1271 (2008 December)
Abstract | Link to Journal | Download Reprint (PDF) | Download Supplemental Material (PDF)
 
205.  
Calibrating excitation light fluxes for quantitative light microscopy in cell biology.
Grünwald D, Shenoy SM, Burke S, Singer RH
Nat Protoc 3(11):1809-1814 (2008 November)
Abstract | Link to Journal | Download Reprint (PDF)
 
204.  
The Dynamics of Mammalian P Body Transport, Assembly and Disassembly In Vivo.
Aizer A, Brody Y, Ler LW, Sonenberg N, Singer RH, Shav-Tal Y
Mol Biol Cell 19(10):4154-4166 (2008 October)
Abstract | Link to Journal | Download Reprint (PDF) | Supplemental Online Information
 
203.  
Highways for mRNA Transport
Singer RH
Cell 134(5):722-723 (2008 September 5)
Abstract | Link to Journal | Download Reprint (PDF)
 
202.  
Feedback regulation between ZBP1 and β-catenin mRNAs in breast cancer cells.
Gu W, Wells AL, Pan F, Singer RH
Mol Cell Biol 28(16):4963-4974 (2008 August)
Abstract | Link to Journal | Download Reprint (PDF)
 
201.  
Nuclear microenvironment in cancer diagnosis and treatment.
Pezo RC, Singer RH
J Cell Biochem 104(6):1953-1963 (2008 August 15)
Abstract | Link to Journal | Download Reprint (PDF)
 
200.  
A role for VICKZ proteins in the progression of colorectal carcinomas: Regulating lamellipodia formation.
Vainer G, Vainer-Mossel E, Pikarsky A, Shenoy SM, Oberman F, Yeffet A, Singer RH, Pikarsky E, Yisraeli JK
J Pathol 215(4):445-456 (2008 August)
Abstract | Link to Journal | Download Reprint (PDF)
 
199.  
Single-Cell Transcription Site Activation Predicts Chemotherapy Response in Human Colorectal Tumors.
Pezo RC, Gandhi SJ, Shirley LA, Pestell RG, Augenlicht LH, Singer RH
Cancer Res 68(13):4977-4982 (2008 July 1)
Abstract | Link to Journal | Download Reprint (PDF)
 
198.  
A Direct Role for FMRP in Activity-Dependent Dendritic mRNA Transport Links Filopodial-Spine Morphogenesis to Fragile X Syndrome.
Dictenberg JB, Swanger SA, Antar LN, Singer RH, Bassell GJ
Dev Cell 14(6):926-939 (2008 June 10)
Abstract | Link to Journal | Download Reprint (PDF)
 
197.  
The Dynamic Range of Transcription.
Darzacq X, Singer RH
Mol Cell 30(5):545-546 (2008 June 5)
Abstract | Link to Journal | Download Reprint (PDF)
 
196.  
Translation of ASH1 mRNA is repressed by Puf6p-Fun12p/eIF5B interaction and released by CK2 phosphorylation.
Deng Y, Singer RH, Gu W
Genes Dev 22(8):1037-1050 (2008 April 15)
Abstract | Link to Journal | Download Reprint (PDF)
 
195.  
Mechanisms and cellular roles of local protein synthesis in mammalian cells.
Rodriguez AJ, Czaplinski K, Condeelis JS, Singer RH
Curr Opin Cell Biol 20(2):144-149 (2008 April)
Abstract | Link to Journal | Download Reprint (PDF)
 
194.  
Myo2p, a class V myosin in budding yeast, associates with a large ribonucleic acid–protein complex that contains mRNAs and subunits of the RNA-processing body.
Chang W, Zaarour RF, Reck-Peterson S, Rinn J, Singer RH, Snyder M, Novick P, Mooseker MS
RNA 14(3):491-502 (2008 March)
Abstract | Link to Journal | Download Reprint (PDF)
 
193.  
Structural basis for the coevolution of a viral RNA–protein complex.
Chao JA, Patskovsky Y, Almo SC, Singer RH
Nat Struct Mol Biol 15(1):103-105 (2008 January)
Abstract | Link to Journal | Download Reprint (PDF) | Download Reprint of Research Highlights (PDF)
 
192.  
Imaging Real-Time Gene Expression in Living Systems.
Wells AL, Condeelis JS, Singer RH, Zenklusen D
Single-Molecule Techniques: A Laboratory Manual, eds Selvin PR and Ha T, 209-238. Cold Spring Harbor Laboratory Press (2007 December)
ISBN: 978-087969775-4
 
191.  
ZBP2 facilitates binding of ZBP1 to β-actin mRNA during transcription.
Pan F, Huttelmaier S, Singer RH, Gu W
Mol Cell Biol 27(23):8340-8351 (2007 December)
Abstract | Link to Journal | Download Reprint (PDF)
 
190.  
The spatial order of transcription in mammalian cells.

Levsky JM, Shenoy SM, Chubb JR, Hall CB, Capodieci P, Singer RH

J Cell Biochem 102(3):609-617 (2007 October 15)
Abstract | Link to Journal | Download Reprint (PDF)
 
189.  
ZBP1 enhances cell polarity and reduces chemotaxis.

Lapidus K, Wyckoff J, Mouneimne G, Lorenz M, Soon L, Condeelis JS, Singer RH

J Cell Sci 120(18):3173-3178 (2007 September 15)
Abstract | Link to Journal | Download Reprint (PDF)
 
188.  
In vivo dynamics of RNA polymerase II transcription.
Darzacq X, Shav-Tal Y, de Turris V, Brody Y, Shenoy SM, Phair RD, Singer RH
Nat Struct Mol Biol 14(9):796-806 (2007 September)
Abstract | Link to Journal | Download Reprint (PDF) | Download Reprint of News & Views (PDF)
 
187.  
QNQKE targeting motif for the SMN-Gemin multiprotein complexin neurons.
Zhang HL, Xing L, Singer RH, Bassell GJ
J Neurosci Res 85(12):2657-2667 (2007 September)
Abstract | Link to Journal | Download Reprint (PDF)
 
186.  
Molecular restoration of archived transcriptional profiles by complementary-template reverse-transcription (CT-RT).
Loudig O, Milova E, Brandwein-Gensler M, Massimi A, Belbin TJ, Childs G, Singer RH, Rohan T, Prystowsky MB
Nucleic Acids Res 35(15):e94 (2007 August)
Abstract | Link to Journal | Download Reprint (PDF)
 
185.  
Yeast Mitochondrial Transcriptomics.
Garcia M, Darzacq X, Devaux F, Singer RH, Jacq C
Methods in Molecular Biology: Mitochondria Practical Protocols, eds Leister D and Herrmann J. Humana Press (2007 June 12)
ISBN: 978-1-58829-667-2
 
184.  
Dissecting Cellular Activity from Single Genes to Single mRNAs.
Darzacq X, Singer RH, Shav-Tal Y
New Frontiers in Ultrasensitive Bioanalysis: Advanced Analytical Chemistry Applications in Nanobiotechnology, Single Molecule Detection, and Single Cell Analysis, ed Xu XN, 29-39. Wiley-Interscience (2007 April 13)
Abstract | Download Reprint (PDF) | ISBN: 978-0-471-74660-7
 
183.  
Imaging mRNA movement from transcription sites to translation sites.
Rodriguez AJ, Condeelis J, Singer RH, Dictenberg JB
Semin Cell Dev Biol 18(2):202-208 (2007 April)
Abstract | Link to Journal | Download Reprint (PDF)
 
182.  
Localized Translation through Messenger RNA Localization.
Gavis ER, Singer RH, Huttelmaier S
Translational Control in Biology and Medicine, eds Mathews MB and Hershey J, 689-718. Cold Spring Harbor Laboratory Press (2007 March)
ISBN: 0-87-969767-9
 
181.  
YRA1 Autoregulation Requires Nuclear Export and Cytoplasmic Edc3p-Mediated Degradation of Its Pre-mRNA.
Dong S, Li C, Zenklusen D, Singer RH, Jacobson A, He F
Mol Cell 25(4):559-573 (2007 February 23)
Abstract | Link to Journal | Download Reprint (PDF)
 
180.  
Mitochondria-associated Yeast mRNAs and the Biogenesis of Molecular Complexes.
Garcia M, Darzacq X, Delaveau T, Jourdren L, Singer RH, Jacq C
Mol Biol Cell 18(2):362-368 (2007 February)
Abstract | Link to Journal | Download Reprint (PDF)
 
179.  
Dynamic association and localization of human H/ACA RNP proteins.
Kittur N, Darzacq X, Roy S, Singer RH, Meier UT
RNA 12(12):2057-2062 (2006 December)
Abstract | Link to Journal | Download Reprint (PDF)
 
178.  
Pathways for mRNA localization in the cytoplasm.
Czaplinski K, Singer RH
Trends Biochem Sci 31(12):687-693 (2006 December)
Abstract | Link to Journal | Download Reprint (PDF)
 
177.  
ZBP1 regulates mRNA stability during cellular stress.
Stöhr N, Lederer M, Reinke C, Meyer S, Hatzfeld M, Singer RH, Huttelmaier S
J Cell Biol 175(4):527-534 (2006 November 20)
Abstract | Link to Journal | Download Reprint (PDF)
 
176.  
Visualization of mRNA translation in living cells.
Rodriguez AJ, Shenoy SM, Singer RH, Condeelis J
J Cell Biol 175(1):67-76 (2006 October 9)
Abstract | Link to Journal | Supplemental Online Information | Download Reprint (PDF)
 
175.  
A peptide motif in Raver1 mediates splicing repression by interaction with the PTB RRM2 domain.
Rideau AP, Gooding C, Simpson PJ, Monie TP, Lorenz M, Huttelmaier S, Singer RH, Matthews S, Curry S, Smith CW
Nat Struct Mol Biol 13(9):839-848 (2006 September)
Abstract | Link to Journal | Download Reprint (PDF) | Download Supplement (PDF)
 
174.  
Multiprotein Complexes of the Survival of Motor Neuron Protein SMN with Gemins Traffic to Neuronal Processes and Growth Cones of Motor Neurons.
Zhang HL, Xing L, Rossoll W, Wichterle H, Singer RH, Bassell GJ
J Neurosci 26(33):8622-8632 (2006 August 15)
Abstract | Link to Journal | Download Reprint (PDF)
 
173.  
Gene expression within a dynamic nuclear landscape.
Shav-Tal Y, Darzacq X, Singer RH
EMBO J 25(15):3469-3479 (2006 August)
Abstract | Link to Journal | Supplemental Online Information | Download Reprint (PDF)
 
172.  
Nucleus and gene regulation.
Pederson T, Singer RH
Curr Opin Cell Biol 18(3):229-230 (2006 June)
Abstract | Link to Journal | Download Reprint (PDF)
 
171.  
Transcriptional pulsing of a developmental gene.
Chubb JR, Trcek T, Shenoy SM, Singer RH
Curr Biol 16(10):1018-1025 (2006 May 23)
Abstract | Link to Journal | Supplemental Online Information | Download Reprint (PDF)
 
170.  
Stepwise RNP assembly at the site of H/ACA RNA transcription in human cells.
Darzacq X, Kittur N, Roy S, Shav-Tal Y, Singer RH, Meier UT
J Cell Biol 173(2):207-219 (2006 April 24)
Abstract | Link to Journal | Download Reprint (PDF)
 
169.  
Developmental timing in Dictyostelium is regulated by the Set1 histone methyltransferase.
Chubb JR, Bloomfield G, Xu Q, Kaller M, Ivens A, Skelton J, Turner BM, Nellen W, Shaulsky G, Kay RR, Bickmore WA, Singer RH
Dev Biol 292(2):519-532 (2006 April 15)
Abstract | Link to Journal | Download Reprint (PDF)
 
168.  
Assembling an intermediate filament network by dynamic cotranslation.
Chang L, Shav-Tal Y, Trcek T, Singer RH, Goldman RD
J Cell Biol 172(5):747-758 (2006 February 27)
Abstract | Link to Journal | Download Reprint (PDF)
 
167.  
Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1.
Huttelmaier S, Zenklusen D, Lederer M, Dictenberg J, Lorenz M, Meng X, Bassell GJ, Condeelis J, Singer RH
Nature 438(7067):512-515 (2005 November 24)
Abstract | Link to Journal | Download Reprint (PDF) | Download Supplement (PDF) |
Download Reprint of News & Views by Dahm & Kiebler (PDF)
| Download Reprint of News & Views by Paquin & Chartrand (PDF)
 
166.  
Single Cell Gene Expression Profiling: Multiplexed Expression Fluorescence in situ Hybridization (FISH): Application to the Analysis of Cultured Cells.
Levsky JM, Braut SA, Singer RH
Cell Biology: A Laboratory Handbook Volume 4, eds Celis JE, et al, 121-130. Academic Press (2005 November 16)
ISBN: 0-12-164730-7
 
165.  
The Great Escape: When Cancer Cells Hijack the Genes for Chemotaxis and Motility.
Condeelis J, Singer RH, Segall JE
Annu Rev Cell Dev Biol 21:695-718 (2005 November)
Abstract | Link to Publisher | Download Reprint (PDF)
 
164.  
In Situ Hybridization to RNA.
Huang S, Singer RH
Basic Methods in Microscopy, eds Spector DL and Goldman RD, 277-290. Cold Spring Harbor Laboratory (2005 October 28)
ISBN: 0-87969-751-2, 0-87969-747-4
 
163.  
Imaging of gene expression in living cells and tissues.
Singer RH, Lawrence DS, Ovryn B, Condeelis J
J Biomed Optics 10(5):0514061-0514069 (2005 September/October)
Abstract | Link to Publisher | Download Reprint (PDF)
 
162.  
RNA localization.
Shav-Tal Y, Singer RH
J Cell Sci 118(18):4077-4081 (2005 September 15)
Abstract | Link to Journal | Poster Insert | Download Reprint (PDF)
 
161.  
Gene expression profiling in single cells within tissue.
Capodieci P, Donovan M, Buchinsky H, Jeffers Y, Cordon-Cardo C, Gerald W, Edelson J, Shenoy SM, Singer RH
Nat Methods 2(9):663-665 (2005 September)
Abstract | Link to Journal | Supplemental Online Information | Download Reprint (PDF)
 
160.  
Localization of all seven messenger RNAs for the actin-polymerization nucleator Arp2/3 complex in the protrusions of fibroblasts.
Mingle LA, Okuhama NN, Shi J, Singer RH, Condeelis J, Liu G
J Cell Sci 118(11):2425-2433 (2005 June 1)
Abstract | Link to Journal | Download Reprint (PDF)
 
159.  
Dynamics of transcription and mRNA export.
Darzacq X, Singer RH, Shav-Tal Y
Curr Opin Cell Biol 17(3):332-339 (2005 June)
Abstract | Link to Journal | Download Reprint (PDF)
 
158.  
Promotion of importin alpha-mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3.
Faul C, Huttelmaier S, Oh J, Hachet V, Singer RH, Mundel P
J Cell Biol 169(3):415-424 (2005 May 9)
Abstract | Link to Journal | Download Reprint (PDF)
 
157.  
Dynamic Sorting of Nuclear Components into Distinct Nucleolar Caps during Transcriptional Inhibition.
Shav-Tal Y, Blechman J, Darzacq X, Montagna C, Dye BT, Patton JG, Singer RH, Zipori D
Mol Biol Cell 16(5):2395-2413 (2005 May)
Abstract | Link to Journal | Download Reprint (PDF)
 
156.  
How and why does beta-actin mRNA target?
Condeelis JS, Singer RH
Biol Cell 97(1):97-110 (2005 January)
Abstract | Link to Journal | Download Reprint (PDF)
 
155.  
Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors.
Wang W, Goswami S, Lapidus K, Wells AL, Wyckoff JB, Sahai E, Singer RH, Segall JE, Condeelis JS
Cancer Res 64(23):8585-8594 (2004 December 1)
Abstract | Link to Journal | Download Reprint (PDF)
 
154.  
She2p Is a Novel RNA Binding Protein with a Basic Helical Hairpin Motif.
Niessing D, Huttelmaier S, Zenklusen D, Singer RH, Burley SK
Cell 119(4):491-502 (2004 November 12)
Abstract | Link to Journal | Download Reprint (PDF)
 
153.  
Imaging of Single mRNAs in the Cytoplasm of Living Cells.
Shav-Tal Y, Shenoy SM, Singer RH
Live Cell Imaging: A Laboratory Manual, eds Goldman RD and Spector DL, 603-615. Cold Spring Harbor Laboratory (2004 October)
ISBN: 0-87969-682-6, 0-87969-683-4
 
152.  
Imaging gene expression in single living cells.
Shav-Tal Y, Singer RH, Darzacq X
Nat Rev Mol Cell Biol 5(10):855-862 (2004 October)
Abstract | Link to Journal | Supplemental Online Information | Download Reprint (PDF)
 
151.  
Dynamics of Single mRNPs in Nuclei of Living Cells.
Shav-Tal Y, Darzacq X, Shenoy SM, Fusco D, Janicki SM, Spector DL, Singer RH
Science 304(5678):1797-1800 (2004 June 18)
Abstract | Link to Journal | Supplemental Online Information | Download Reprint (PDF)
 
150.  
A new yeast PUF family protein, Puf6p, represses ASH1 mRNA translation and is required for its localization.
Gu W, Deng Y, Zenklusen D, Singer RH
Genes Dev 18(12):1452-1465 (15 June 2004)
Abstract | Link to Journal | Download Reprint (PDF)
 
149.  
Imaging sites of N-WASP activity in lamellipodia and invadopodia of carcinoma cells.
Lorenz M, Yamaguchi H, Wang Y, Singer RH, Condeelis J
Curr Biol 14(8):697-703 (20 April 2004)
Abstract | Link to Journal | Download Reprint (PDF) | Download Supplement (PDF)
 
148.  
From Silencing to Gene Expression: Real-Time Analysis in Single Cells.
Janicki SM, Tsukamoto T, Salghetti SE, Tansey WP, Sachidanandam R, Prasanth KV, Ried T, Shav-Tal Y, Bertrand E, Singer RH, Spector DL
Cell 116(5):683-698 (2004 March 5)
Abstract | Link to Journal | Download Reprint (PDF)
 
147.  
Measurement of barbed ends, actin polymerization, and motility in live carcinoma cells after growth factor stimulation.
Lorenz M, DesMarais V, Macaluso F, Singer RH, Condeelis J
Cell Motil Cytoskeleton 57(4):207-217 (2004 April)
Abstract | Link to Journal | Download Reprint (PDF)
 
146.  
Imaging of Single mRNAs in the Cytoplasm of Living Cells.
Fusco D, Bertrand E, Singer RH
RNA Trafficking and Nuclear Structure Dynamics, ed Jeanteur P, 135-150. Springer-Verlag (2004 February 29)
Prog Mol Subcell Biol 35:135-150. (2004)
Download Reprint (PDF) | ISBN: 3-540-40451-1
 
145.  
The PTB interacting protein raver1 regulates alpha-tropomyosin alternative splicing.
Gromak N, Rideau A, Southby J, Scadden AD, Gooding C, Huttelmaier S, Singer RH, Smith CW
EMBO J 22(23):6356-6364 (2003 December 1)
Abstract | Link to Journal | Download Reprint (PDF)
 
144.  
RNA asymmetric distribution and daughter/mother differentiation in yeast.
Darzacq X, Powrie E, Gu W, Singer RH, Zenklusen D
Curr Opin Microbiol 6(6):1-7 (2003 December)
Abstract | Link to Journal | Download Reprint (PDF)
 
143.  
Localization of a ß-Actin Messenger Ribonucleoprotein Complex with Zipcode-Binding Protein Modulates the Density of Dendritic Filopodia and Filopodial Synapses.
Eom T, Antar LN, Singer RH, Bassell GJ
J Neurosci 23(32):10433-10444 (2003 November 12)
Abstract | Link to Journal | Download Reprint (PDF)
 
142.  
RNA Localization and Signal Transduction.
Latham V, Singer RH
Handbook of Cell Signalling Volume 3, ed Bradshaw RA and Dennis EA, 293-297. Academic Press (2003 November 7)
Download Reprint (PDF) | ISBN: 0-12-124546-2
 
141.  
   
RNA localization: visualization in real-time.
Singer RH
Curr Biol 13(17):R673-R675 (2003 September 2)
Abstract | Link to Journal | Download Reprint (PDF)
 
140.  
Role of the parafusin orthologue, PRP1, in microneme exocytosis and cell invasion in Toxoplasma gondii.
Matthiesen SH, Shenoy SM, Kim K, Singer RH, Satir BH
Cell Microbiol 5(9):613-624 (2003 September)
Abstract | Link to Journal | Download Reprint (PDF)
 
139.  
Active transport of the survival motor neuron protein and the role of exon-7 in cytoplasmic localization.
Zhang HL, Pan F, Hong D, Shenoy SM, Singer RH, Bassell GJ
J Neurosci 23(16):6627-6637 (2003 July 23)
Abstract | Link to Journal | Supplemental Online Information | Download Reprint (PDF)
 
138.  
Fluorescence in situ hybridization: past, present and future.
Levsky JM, Singer RH
J Cell Sci 116(14):2833-2838 (2003 July 15)
Abstract | Link to Journal | Download Reprint (PDF)
 
137.  
Asymmetric Distribution of Nuclear Pore Complexes and the Cytoplasmic Localization of ß2-Tubulin mRNA in Chlamydomonas reinhardtii.
Colón-Ramos DA, Salisbury JL, Sanders MA, Shenoy SM, Singer RH, Garciá-Blanco MA
Dev Cell 4(6):941-952 (2003 June)
Abstract | Link to Journal | Download Reprint (PDF)
 
136.  
Activity-Dependent Trafficking and Dynamic Localization of Zipcode Binding Protein 1 and beta-Actin mRNA in Dendrites and Spines of Hippocampal Neurons.
Tiruchinapalli DM, Oleynikov Y, Kelic S, Shenoy SM, Hartley A, Stanton PK, Singer RH, Bassell GJ
J Neurosci 23(8):3251-3261 (2003 April 15)
Abstract | Link to Journal | Supplemental Online Information | Download Reprint (PDF)
 
135.  
Visualization of single molecules of mRNA in situ.
Femino AM, Fogarty K, Lifshitz LM, Carrington W, Singer RH
Methods Enzymol 361:245-304 (2003)
Link to Publisher | Download Reprint (PDF)
 
134.  
Real-time visualization of ZBP1 association with beta-actin mRNA during transcription and localization.
Oleynikov Y, Singer RH
Curr Biol 13(3):199-207 (2003 February 4)
Abstract | Link to Journal | Supplemental Online Information | Download Reprint (PDF)
 
133.  
Single mRNA molecules demonstrate probabilistic movement in living mammalian cells.
Fusco D, Accornero N, Lavoie B, Shenoy SM, Blanchard JM, Singer RH, Bertrand E
Curr Biol 13(2):161-167 (2003 January 21)
Abstract | Link to Journal | Supplemental Online Information | Download Reprint (PDF)
 
132.  
Two ZBP1 KH domains facilitate beta-actin mRNA localization, granule formation, and cytoskeletal attachment.
Farina KL, Huttelmaier S, Musunuru K, Darnell R, Singer RH
J Cell Biol 160(1):77-87 (2003 January 6)
Abstract | Link to Journal | Download Reprint (PDF)
 
131.  
Gene expression and the myth of the average cell.
Levsky JM, Singer RH
Trends Cell Biol 13(1):4-6 (2003 January)
Abstract | Link to Journal | Download Reprint (PDF)
 
130.  
Asymmetric sorting of ash1p in yeast results from inhibition of translation by localization elements in the mRNA.
Chartrand P, Meng XH, Huttelmaier S, Donato D, Singer RH
Mol Cell 10(6):1319-1330 (2002 December)
Abstract | Link to Journal | Download Reprint (PDF)
 
129.  
Single cell behavior in metastatic primary mammary tumors correlated with gene expression patterns revealed by molecular profiling.
Wang W, Wyckoff JB, Frohlich VC, Oleynikov Y, Huttelmaier S, Zavadil J, Cermak L, Bottinger EP, Singer RH, White JG, Segall JE, Condeelis JS
Cancer Res 62(21):6278-6288 (2002 November 1)
Abstract | Link to Journal | Download Reprint (PDF) | Download Errata (PDF)
 
128.  
Novel detection and differential utilization of a c-myc transcriptional block in colon cancer chemoprevention.
Wilson AJ, Velcich A, Arango D, Kurland AR, Shenoy SM, Pezo RC, Levsky JM, Singer RH, Augenlicht LH
Cancer Res 62(21):6006-6010 (2002 November 1)
Abstract | Link to Journal | Download Reprint (PDF)
 
127.  
The nuclear connection in RNA transport and localization.
Farina KL, Singer RH
Trends Cell Biol 12(10):466-472 (2002 October)
Abstract | Link to Journal | Download Reprint (PDF)
 
126.  
An active precursor in assembly of yeast nuclear ribonuclease P.
Srisawat C, Houser-Scott F, Bertrand E, Xiao S, Singer RH, Engelke DR
RNA 8(10):1348-1360 (2002 October)
Abstract | Link to Journal | Download Reprint (PDF)
 
125.  
Single-cell gene expression profiling.
Levsky JM, Shenoy SM, Pezo RC, Singer RH
Science 297(5582):836-840 (2002 August 2)
Abstract | Link to Journal | Supplemental Online Information | Download Reprint (PDF)
 
124.  
Interactions of elongation factor 1alpha with F-actin and beta-actin mRNA: implications for anchoring mRNA in cell protrusions.
Liu G, Grant WM, Persky D, Latham VM Jr, Singer RH, Condeelis J
Mol Biol Cell 13(2):579-592 (2002 February)
Abstract | Link to Journal | Download Reprint (PDF)
 
123.  
A predominantly nuclear protein affecting cytoplasmic localization of beta-actin mRNA in fibroblasts and neurons.
Gu W, Pan F, Zhang H, Bassell GJ, Singer RH
J Cell Biol 156(1):41-51 (2002 January 7)
Abstract | Link to Journal | Download Reprint (PDF)
 
122.  
A parafusin-related Toxoplasma protein in Ca2+-regulated secretory organelles.
Matthiesen SH, Shenoy SM, Kim K, Singer RH, Satir BH
Eur J Cell Biol 80(12):775-783 (2001 December)
Abstract | Link to Journal | Supplemental Online Information | Download Reprint (PDF)
 
121.  
Raver1, a dual compartment protein, is a ligand for PTB/hnRNPI and microfilament attachment proteins.
Huttlemaier S, Illenberger S, Grosheva I, Rudiger M, Singer RH, Jockusch BM
J Cell Biol 155(5):775-86 (2001 November 26)
Abstract | Link to Journal | Download Reprint (PDF)
 
120.  
Neurotrophin-induced transport of a beta-actin mRNP complex increases beta-actin levels and stimulates growth cone motility.
Zhang HL, Eom T, Oleynikov Y, Shenoy SM , Liebelt DA, Dictenberg JB, Singer RH, Bassell GJ
Neuron 31(2):261-275 (2001 August 2)
Abstract | Link to Journal | Supplemental Online Information | Download Reprint (PDF)
 

119.

 
A Rho-dependent signaling pathway operating through myosin localizes beta-actin mRNA in fibroblasts.
Latham VM, Yu EH, Tullio AN, Adelstein RS, Singer RH
Curr Biol 11(13):1010-1016 (2001 July 10)
Abstract | Link to Journal | Download Reprint (PDF)
 
118.  
RNP localization and transport in yeast.
Chartrand P, Singer RH, Long RM
Annu Rev Cell Dev Biol 17:297-310 (2001)
Abstract | Link to Publisher | Download Reprint (PDF)
 
117.  
The physiological significance of beta -actin mRNA localization in determining cell polarity and directional motility.
Shestakova EA, Singer RH, Condeelis J
Proc Natl Acad Sci U S A 98(13):7045-7050 (2001 June 19)
Abstract | Link to Journal | Download Reprint (PDF)
 
116.  
Terminal minihelix: A novel RNA motif that directs polymerase III transcripts to the cell cytoplasm.
Gwizdek C, Bertrand E, Dargemont C, Lefebvre JC, Blanchard JM, Singer RH, Doglio A
J Biol Chem 276(28):25910-25918 (2001 July 13)
Abstract | Link to Journal | Download Reprint (PDF)
 
115.  
An exclusively nuclear RNA-binding protein affects asymmetric localization of ASH1 mRNA and Ash1p in yeast.
Long RM, Gu W, Meng X, Gonsalvez G, Singer RH, Chartrand P
J Cell Biol 153(2):307-318 (2001 April 16)
Abstract | Link to Journal | Download Reprint (PDF)
 
114.  
Neuronal RNA localization and the cytoskeleton.
Bassell GJ, Singer RH
Results Probl Cell Differ 34:41-56 (2001)
Link to Publisher
 
113.  
Determination of Transgenic Loci by Expression FISH.
Fan Y, Braut SA, Lin Q, Singer RH, Skoultchi AI
Genomics 71(1):66-69 (2001 January 1)
Abstract | Link to Journal | Download Reprint (PDF)
 
112.  
The odyssey of a regulated transcript.
Vilardell J, Chartrand P, Singer RH, Warner JR
RNA 6(12):1773-1780 (2000 December)
Abstract | Link to Journal | Download Reprint (PDF)
 
111.  
She2p is a novel RNA-binding protein that recruits the Myo4p-She3p complex to ASH1 mRNA.
Long RM, Gu W, Lorimer E, Singer RH, Chartrand P
EMBO J 19(23):6592-6601 (2000 December 1)
Abstract | Link to Journal | Download Reprint (PDF)
 
110.  
A CBF5 mutation that disrupts nucleolar localization of early tRNA biosynthesis in yeast also suppresses tRNA gene-mediated transcriptional silencing.
Kendall A, Hull MW, Bertrand E, Good PD, Singer RH, Engelke DR
Proc Natl Acad Sci U S A 97(24):13108-13113 (2000 November 21)
Abstract | Link to Journal | Download Reprint (PDF)
 
109.  
Sensitive and high-resolution detection of RNA in situ.
Chartrand P, Bertrand E, Singer RH, Long RM
Methods Enzymol 318:493-506 (2000 June 16)
Link to Publisher | Download Reprint (PDF)
 
108.  
Trypanosoma cruzi infection affects actin mRNA regulation in heart muscle cells.
Pereira MC, Singer RH, de Meirelles MN
J Eukaryot Microbiol 47(3):271-279 (2000 May-June)
Abstract | Link to Journal | Download Reprint (PDF)
 
107.  
Ultrastructural distribution of poly (A)+ RNA during Trypanosoma cruzi-cardiomyocyte interaction in vitro: a quantitative analysis of the total mRNA content by in situ hybridization.
Pereira MC, Singer RH, de Meirelles MN
J Eukaryot Microbiol 47(3):264-270 (2000 May-June)
Abstract | Link to Journal | Download Reprint (PDF)
 
106.  
Trypanosoma cruzi-cardiomyocytes: new contributions regarding a better understanding of this interaction.
Meirelles MN, Pereira MC, Singer RH, Soeiro MN, Garzoni LR, Silva DT, Barbosa HS, Araujo-Jorge TC, Masuda MO, Capella MA, Lopes AG, Vermelho AB
Mem Inst Oswaldo Cruz 94(Suppl 1):149-152 (1999)
Abstract | Link to Journal | Download Reprint (PDF)
 
105.  
Neurotrophin Regulation of beta-Actin mRNA and Protein Localization within Growth Cones.
Zhang H, Singer RH, Bassell GJ
J Cell Biol 147(1):59-70 (1999 October 4)
Abstract | Link to Journal | Download Reprint (PDF)
 
104.  
In Situ Reverse Transcription for Detection of Hybridization between Oligonucleotides and Their Intracellular Targets.
Politz JC, Singer RH
Methods 18(3):281-285 (1999 July)
Abstract | Link to Journal | Download Reprint (PDF)
 
103.  
A small nucleolar RNA:ribozyme hybrid cleaves a nucleolar RNA target in vivo with near-perfect efficiency.
Samarsky DA, Ferbeyre G, Bertrand E, Singer RH, Cedergren R, Fournier MJ
Proc Natl Acad Sci U S A 96(12):6609-14 (1999 June 8)
Abstract | Link to Journal | Download Reprint (PDF)
 
102.  
Short Dysfunctional Telomeres Impair Tumorigenesis in the INK4D2/3 Cancer-Prone Mouse.
Greenberg RA, Chin L, Femino A, Lee KH, Gottlieb GJ, Singer RH, Greider CW, DePinho RA
Cell 97(4):515-525 (1999 May 14)
Abstract | Link to Journal | Download Reprint (PDF)
 
101.  
Correlation of ß-Actin Messenger RNA Localization with Metastatic Potential in Rat Adenocarcinoma Cell Lines.
Shestakova EA, Wyckoff J, Jones J, Singer RH, Condeelis J
Cancer Res 59(6):1202-1205 (1999 March 15)
Abstract | Link to Journal | Download Reprint (PDF)
 
100.  
Structural elements required for the localization of ASH1 mRNA and of a green fluorescent protein reporter particle in vivo.
Chartrand P, Meng X, Singer RH, Long RM
Curr Biol 9(6):333-338 (1999 March 15)
Abstract | Link to Journal | Download Reprint (PDF)
 
99.  
Movement of nuclear poly(A) RNA throughout the interchromatin space in living cells.
Politz JC, Tuft RA, Pederson T, Singer RH
Curr Biol 9(6):285-291 (1999 March 5)
Abstract | Link to Journal | Download Reprint (PDF)
 
98.  
The travels of mRNAs through all cells large and small.
Bassell GJ, Oleynikov Y, Singer RH
FASEB J 13(3):447-454 (1999 March)
Link to Journal | Download Reprint (PDF)
 
97.  
3'-End modification of the adenoviral VA1 gene affects its expression in human cells:  consequences for the design of chimeric VA1 RNA ribozymes.
Barcellini-Couget S, Fenard D, Bertrand E, Singer RH, Lefebvre JC, Doglio A
Antisense Nucleic Acid Drug Dev 8(5):379-90 (1998 October)
Abstract | Link to Journal
 

96.

 
Localization of ASH1 mRNA Particles in Living Yeast.
Bertrand E, Chartrand P, Schaefer M, Shenoy SM, Singer RH, Long RM
Mol Cell 2(4):437-445 (1998 October)
Abstract | Link to Journal | Supplemental Online Information | Download Reprint (PDF)
 
95.  
RNA localization: different zipcodes, same postman?
Oleynikov Y, Singer RH
Trends Cell Biol 8(10):381-383 (1998 October)
Link to Journal | Download Reprint (PDF)
 
94.  
Nucleolar localization of early tRNA processing.
Bertrand E, Houser-Scott F, Kendall A, Singer RH, Engelke DR
Genes Dev 12(16):2463-2468 (1998 August 15)
Abstract | Link to Journal | Download Reprint (PDF)
 
93.  
The snoRNA box C/D motif directs nucleolar targeting and also couples snoRNA synthesis and localization.
Samarsky DA, Fournier MJ, Singer RH, Bertrand E
EMBO J 17(13):3747-3757 (1998 July 1)
Abstract | Link to Journal | Download Reprint (PDF)
 
92.  
Triplet-repeat transcripts: A role for RNA in disease.
Singer RH
Science 280(5364):696-697 (1998 May 1)
Link to Journal
 
91.  
Visualization of Single RNA Transcripts in Situ
Femino AM, Fay FS, Fogarty K, Singer RH
Science 280(5363):585-590 (1998 April 24)
Abstract | Link to Journal | Supplemental Online Information | Download Reprint (PDF)
 
90.  
Integrin binding and mechanical tension induce movement of mRNA and ribosomes to focal adhesions.
Chicurel ME, Singer RH, Meyer CJ, Ingber DE
Nature 392(6677):730-733 (1998 April 16)
Link to Journal | Download Reprint (PDF)
 
89.  
Sorting of beta-actin mRNA and protein to neurites and growth cones in culture.
Bassell GJ, Zhang H, Byrd AL, Femino AM, Singer RH, Taneja KL, Lifshitz LM, Herman IM, Kosik KS
J Neurosci 18(1):251-265 (1998 January 1)
Abstract | Link to Journal | Download Reprint (PDF)
 
88.  
In Situ Hybridization to RNA.
et al, Singer RH
Cells : A Laboratory Manual, eds Spector DL, Goldman RD and Leinwand LA. Cold Spring Harbor Laboratory (1997 December 1)
ISBN: 0-87969-521-8, 0-87969-522-6
 
87.  
Compartmentalization of eukaryotic gene expression: causes and effects.
Singer RH, Green MR
Cell 91(3):291-294 (1997 October 31)
Link to Journal | Download Reprint (PDF)
 
86.  
Mating Type Switching in Yeast Controlled by Asymmetric Localization of ASH1 mRNA.
Long RM, Singer RH, Meng X, Gonzalez I, Nasmyth K, Jansen RP
Science 277(5324):383-387 (1997 July 18)
Abstract | Link to Journal | Download Reprint (PDF)
 
85  
Expansion of a CUG trinucleotide repeat in the 3' untranslated region of myotonic dystrophy protein kinase transcripts results in nuclear retention of transcripts.
Davis BM, McCurrach ME, Taneja KL, Singer RH, Housman DE
Proc Natl Acad Sci U S A 94(14):7388-7393 (1997 July 8)
Abstract | Link to Journal | Download Reprint (PDF)
 
84.  
Nuclear domains of the RNA subunit of RNase P.
Jacobson MR, Cao LG, Taneja K, Singer RH, Wang YL, Pederson T
J Cell Sci 110(7):829-837 (1997 April)
Abstract | Link to Journal | Download Reprint (PDF)
 
83.  
Characterization of a beta-actin mRNA zipcode-binding protein.
Ross AF, Oleynikov Y, Kislauskis EH, Taneja KL, Singer RH
Mol Cell Biol 17(4):2158-2165 (1997 April)
Abstract | Link to Journal | Download Reprint (PDF)
 
82.  
beta-Actin messenger RNA localization and protein synthesis augment cell motility.
Kislauskis EH, Zhu X, Singer RH
J Cell Biol 136(6):1263-1270 (1997 March 24)
Abstract | Link to Journal | Download Reprint (PDF)
 
81.  
The intracellular RNA sorting system: Postal zones, zip codes, mail bags and mail boxes.
Steward O, Singer RH

In mRNA Metabolism & Post-Transcriptional Gene Regulation, ed Harford J and Morris D. Wiley-Liss (1997 March)

 

 
80.  
Quantitative digital analysis of diffuse and concentrated nuclear distributions of nascent transcripts, SC35 and poly(A).
Fay FS, Taneja KL, Shenoy S, Lifshitz L, Singer RH
Exp Cell Res 231(1):27-37 (1997 February 25)
Abstract | Link to Journal | Download Reprint (PDF)
 
79.  
mRNA and cytoskeletal filaments.
Bassell G, Singer RH
Curr Opin Cell Biol 9(1):109-115 (1997 February)
Abstract | Link to Journal | Download Reprint (PDF)
 
78.  
RNA: traffic report
Singer RH
Trends Cell Biol 6(12):486-489 (1996 December)
Link to Journal | Download Reprint (PDF)
 
77.  
Human immunodeficiency virus detection in lymph nodes by image analysis of in situ hybridization: basis of a diagnostic test for cadaveric donors.
Mathijs JM, Shenoy SM, Singer RH
Transplant Proc 28(5):2945-2949 (1996 October)
Link to Journal
 
76.  
Triplet repeats and human disease.
Singer RH
Mol Med Today 2(2):65-69 (1996 February)
Abstract | Link to Journal | Download Reprint (PDF)
 
75.  
Characterization of hybridization between synthetic oligodeoxynucleotides and RNA in living cells.
Politz JC, Taneja KL, Singer RH
Nucleic Acids Res 23(24):4946-4953 (1995 December 25)
Abstract | Link to Journal | Download Reprint (PDF)
 
74.  
Spatial consequences of defective processing of specific yeast mRNAs revealed by fluorescent in situ hybridization.
Long RM, Elliott DJ, Stutz F, Rosbash M, Singer RH
RNA 1(10):1071-1078 (1995 December)
Abstract | Link to Journal | Download Reprint (PDF)
 
73.  
Foci of trinucleotide repeat transcripts in nuclei of myotonic dystrophy cells and tissues.
Taneja KL, McCurrach M, Schalling M, Housman D, Singer RH
J Cell Biol 128(6):995-1002 (1995 March)
Abstract | Link to Journal | Download Reprint (PDF)
 
72.  
The mechanism of mRNA localization: its effect on cell polarity.
Kislauskis EH, Ross A, Latham VM, Zhu X-C, Bassell GJ, Taneja KL, Singer RH

In Localized RNAs, ed Lipshitz H. Springer-Verlag Telos (1995 January)

 

 
71.  
Localization of pre-mRNA splicing in mammalian nuclei.
Zhang G, Taneja KL, Singer RH, Green MR
Nature 372(6508):809-812 (1994 December 22)
Abstract | Link to Journal | Download Reprint (PDF)
 
70.  
Sequences responsible for intracellular localization of beta-actin messenger RNA also affect cell phenotype.
Kislauskis EH, Zhu X, Singer RH
J Cell Biol 127(2):441-451 (1994 October)
Abstract | Link to Journal | Download Reprint (PDF)
 
69.  
Actin filaments and the spatial positioning of mRNAs.
Bassell GJ, Taneja KL, Kislauskis EH, Sundell CL, Powers CM, Ross A, Singer RH

In Actin: Biophysics, Biochemistry and Cell Biology (Advances in Experimental Medicine and Biology, 358), ed Higgins P. Plenum Pub Corp (1994 September)

 

 
68.  
Localization of HIV RNA in mitochondria of infected cells: potential role in cytopathogenicity.
Somasundaran M, Zapp ML, Beattie LK, Pang L, Byron KS, Bassell GJ, Sullivan JL, Singer RH
J Cell Biol 126(6):1353-1360 (1994 September)
Abstract | Link to Journal | Download Reprint (PDF)
 
67.  
Beta-actin mRNA localization is regulated by signal transduction mechanisms.
Latham VM Jr, Kislauskis EH, Singer RH, Ross AF
J Cell Biol 126(5):1211-1219 (1994 September)
Abstract | Link to Journal | Download Reprint (PDF)
 
66.  
Single mRNAs visualized by ultrastructural in situ hybridization are principally localized at actin filament intersections in fibroblasts.
Bassell GJ, Powers CM, Taneja KL, Singer RH
J Cell Biol 126(4):863-876 (1994 August)
Abstract | Link to Journal | Download Reprint (PDF)
 
65.  
Association of poly(A) mRNA with microtubules in cultured neurons.
Bassell GJ, Singer RH, Kosik KS
Neuron 12(3):571-582 (1994 March)
Abstract | Link to Journal | Download Reprint (PDF)
 
64.  
Actin filaments and the spatial positioning of mRNAS.
Bassell GJ, Taneja KL, Kislauskis EH, Sundell CL, Powers CM, Ross A, Singer RH
Adv Exp Med Biol 358:183-189 (1994)
 
 
63.  
RNA travel: tracks from DNA to cytoplasm.
Rosbash M, Singer RH
Cell 75(3):399-401 (1993 November 5)
Link to Journal | Download Reprint (PDF)
 
62.  
RNA zipcodes for cytoplasmic addresses.
Singer RH
Curr Biol 3(10):719-721 (1993)
Link to Journal | Download Reprint (PDF)
 
61.  
Isoform-specific 3'-untranslated sequences sort alpha-cardiac and beta-cytoplasmic actin messenger RNAs to different cytoplasmic compartments.
Kislauskis EH, Li Z, Singer RH, Taneja KL
J Cell Biol 123(1):165-172 (1993 October)
Abstract | Link to Journal | Download Reprint (PDF)
 
60.  
Spatial organization of mRNA within cells.
Singer RH
J Cell Biochem 52(2):125-126 (1993 June)
Link to Journal | Download Reprint (PDF)
 
59.  
Gene expression at single cell resolution associated with development of the bone cell phenotype: ultrastructural and in situ hybridization analysis.
Pockwinse SM, Lawrence JB, Singer RH, Stein JL, Lian JB, Stein GS
Bone 14(3):347-352 (1993 May)
Link to Journal | Download Reprint (PDF)
 
58.  
Determinants of mRNA localization.
Kislauskis EH, Singer RH
Curr Opin Cell Biol 4(6):975-978 (1992 December)
Abstract | Link to Journal | Download Reprint (PDF)
 
57.  
Poly(A) RNA codistribution with microfilaments: evaluation by in situ hybridization and quantitative digital imaging microscopy.
Taneja KL, Lifshitz LM, Fay FS, Singer RH
J Cell Biol 119(5):1245-1260 (1992 December)
Abstract | Link to Journal | Download Reprint (PDF)
 
56.  
Ultrastructural in situ hybridization using immunoglod.
Bassell G, Singer R
In Immunoelectron microscopy in virus diagnosis and research, eds Hyatt AD and Eaton BT. CRC Press (1992 November 10)

 

 
55.  
The cytoskeleton and mRNA localization.
Singer RH
Curr Opin Cell Biol 4(1):15-19 (1992 February)
Abstract | Link to Journal | Download Reprint (PDF)
 
54.  
Fluorescent detection of nuclear RNA and DNA: implications for genome organization.
Johnson CV, Singer RH, Lawrence JB
Methods Cell Biol 35:73-99 (1991)
 
 
53.  
Requirement of microfilaments in sorting of actin messenger RNA.
Sundell CL, Singer RH
Science 253(5025):1275-1277 (1991 Sep 13)
Abstract | Link to Journal | Download Reprint (PDF)
 
52.  
New Ways of Looking Within Cells. (Part II)
Singer RH (Editor)
Semin Cell Biol 2(3):145-192 (1991 June)
 
 
51.  
Localizing DNA and RNA within nuclei and chromosomes by fluorescence in situ hybridization.
McNeil JA, Johnson CV, Carter KC, Singer RH, Lawrence JB
Genet Anal Tech Appl 8(2):41-58 (1991 April)
Abstract | Download Reprint (PDF)
 
50.  
Spatial organization of nucleic acid sequences within cells.
Lawrence JB, Singer RH
Semin Cell Biol 2(2):83-101 (1991 April)
Abstract | Link to Journal
 
49.  
New Ways of Looking Within Cells. (Part I)
Singer RH (Editor)
Semin Cell Biol 2(2):81-140 (1991 April)
 
 
48.  
Distribution of myosin heavy chain mRNA in embryonic muscle tissue visualized by ultrastructural in situ hybridization.
Pomeroy ME, Lawrence JB, Singer RH, Billings-Gagliardi S
Dev Biol 143(1):58-67 (1991 January)
Abstract | Link to Journal | Download Reprint (PDF)
 
47.  
Actin mRNA localizes in the absence of protein synthesis.
Sundell CL, Singer RH
J Cell Biol 111(6):2397-2403 (1990 December)
Abstract | Link to Journal | Download Reprint (PDF)
 
46.  
Detection and localization of actin mRNA isoforms in chicken muscle cells by in situ hybridization using biotinated oligonucleotide probes.
Taneja KL, Singer RH
J Cell Biochem 44(4):241-252 (1990 December)
Abstract | Link to Journal | Download Reprint (PDF)
 
45.  
Interphase and metaphase resolution of different distances within the human dystrophin gene.
Lawrence JB, Singer RH, McNeil JA
Science 249(4971):928-932 (1990 August 24)
Abstract | Link to Journal | Download Reprint (PDF)
 
44.  
Subcellular localization of low-abundance human immunodeficiency virus nucleic acid sequences visualized by fluorescence in situ hybridization.
Lawrence JB, Marselle LM, Byron KS, Johnson CV, Sullivan JL, Singer RH
Proc Natl Acad Sci U S A 87(14):5420-5424 (1990 July)
Abstract | Link to Journal | Download Reprint (PDF)
 
43.  
Detection of HIV in Clinical Specimens.
Singer R, Byron K, Lawrence JB, Sullivan JL, Yin S and Lederman L
In Techniques in HIV Research, eds Aldovini A and Walker B. Oxford Univ Pr (1990 May)

 

 
42.  
Diagnostic Applications of Non-Isotopic in situ Hybridization for HIV or EBV Nucleic Acids.
Singer R, Lawrence J, Bashir R, Byron K, Sullivan J
In Modern Pathology of AIDS and Other Retroviral Infections, ed Haase AT, et al, 29-41. S. Karger Publishing (1990 March)

 

 
41.  
Progress Toward Ultrastructural Identification of Individual mRNAs in Thin Section: Myosin heavy-chain mRNA in Developing Myotubes.
Silva F, Lawrence JB, Singer RH
Techniques in Immunocytochemistry 4, ed Bullock GR and Petrusz P, 147-164. Academic Press (1989)
 
 
40.  
Human type II collagen gene (COL2A1) assigned to chromosome 12q13.1-q13.2 by in situ hybridization with biotinylated DNA probe.
Takahashi E, Hori T, Lawrence JB, McNeil J, Singer RH, O'Connell P, Leppert M, White R
Jinrui Idengaku Zasshi (Jpn J Hum Genet) 34(4):307-311 (1989 December)
Abstract
 
39.  
Detection of Epstein-Barr virus by in situ hybridization. Progress toward development of a nonisotopic diagnostic test.
Bashir R, Hochberg F, Singer RH
Am J Pathol 135(6):1035-1044 (1989 December)
Abstract | Link to Journal
 
38.  
Detection of HIV-1-infected cells from patients using nonisotopic in situ hybridization.
Singer RH, Byron KS, Lawrence JB, Sullivan JL
Blood 74(6):2295-2301 (1989 November 1)
Abstract | Link to Journal | Download Reprint (PDF)
 
37.  
Detection of Epstein-Barr Virus in CNS Lymphomas by in situ Hybridization.
Bashir RM, Harris NL, Hochberg FH, Singer RH
Neurology 39(6):813-817 (1989 June)
Abstract | Link to Journal | Download Reprint (PDF)
 
36.  
Ultrastructural visualization of cytoskeletal mRNAs and their associated proteins using double-label in situ hybridization.
Singer RH, Langevin GL, Lawrence JB
J Cell Biol 108(6):2343-2353 (1989 June)
Abstract | Link to Journal | Download Reprint (PDF)
 
35.  
Highly localized tracks of specific transcripts within interphase nuclei visualized by in situ hybridization.
Lawrence JB, Singer RH, Marselle LM
Cell 57(3):493-502 (1989 May 5)
Abstract | Link to Journal | Download Reprint (PDF)
 
34.  
Temporal resolution and sequential expression of muscle-specific genes revealed by in situ hybridization.
Lawrence JB, Taneja K, Singer RH
Dev Biol 133(1):235-246 (1989 May)
Abstract | Link to Journal | Download Reprint (PDF)
 
33.  
Strategies for ultrastructural visualization of biotinated probes hybridized to messenger RNA in situ.
Singer RH, Lawrence JB, Silva F, Langevin GL, Pomeroy M, Billings-Gagliardi S
Curr Top Microbiol Immunol 143:55-69 (1989)
Abstract
 
32.  
Sensitive, high-resolution chromatin and chromosome mapping in situ: presence and orientation of two closely integrated copies of EBV in a lymphoma line.
Lawrence JB, Villnave CA, Singer RH
Cell 52(1):51-61 (1988 January 15)
Abstract | Link to Journal | Download Reprint (PDF)
 
31.  
Intracellular distribution of histone mRNAs in human fibroblasts studied by in situ hybridization.
Lawrence JB, Singer RH, Villnave CA, Stein JL, Stein GS
Proc Natl Acad Sci U S A 85(2):463-467 (1988 January)
Abstract | Link to Journal | Download Reprint (PDF)
 
30.  
Double Labeling in situ Hybridization Using Non-Isotopic and Isotopic Detection.
Singer RH, Lawrence JB, Langevin GL, Rashtchian RN, Johnson CA, Cremer T, Tesin D, Manuelidis L, Ward DC
Acta Histochem Cytochem 20:589-598 (1987)
Link to Journal
 
29.  
Use of oligodeoxynucleotide probes for quantitative in situ hybridization to actin mRNA.
Taneja K, Singer RH
Anal Biochem 166(2):389-398 (1987 November 1)
Abstract | Link to Journal | Download Reprint (PDF)
 
28.  
Amino acid sequences that determine the nuclear localization of yeast histone 2B.
Moreland RB, Langevin GL, Singer RH, Garcea RL, Hereford LM
Mol Cell Biol 7(11):4048-4057 (1987 November)
Abstract | Link to Journal | Download Reprint (PDF)
 
27.  
Toward a Rapid and Sensitive in situ Hybridization Methodology Using Isotopic and Non-Isotopic Probes.
Singer RH, Lawrence JB, Rashtchian RN
In In situ Hybridization: Application to the Central Nervous System, ed Valentino K, et al, 71-96. Oxford University Press: New York (1986)

 

 
26.  
Location of a polypeptide sequence within the alpha-subunit of the acetylcholine receptor containing the cholinergic binding site.
Oblas B, Singer RH, Boyd ND
Mol Pharmacol 29(6):649-656 (1986 June)
Abstract | Link to Journal | Download Reprint (PDF)
 
25.  
Optimization of in situ Hybridization Using Isotopic and Non-Isotopic Detection Methods.
Singer RH, Lawrence JB, Villnave C
BioTechniques 4(3):230-250 (1986 May/June)
Link to Journal
 
24.  
Intracellular localization of messenger RNAs for cytoskeletal proteins.
Lawrence JB, Singer RH
Cell 45(3):407-415 (1986 May 9)
Abstract | Link to Journal | Download Reprint (PDF)
 
23.  
Quantitative analysis of in situ hybridization methods for the detection of actin gene expression.
Lawrence JB, Singer RH
Nucleic Acids Res 13(5):1777-1799 (1985 March 11)
Abstract | Link to Journal | Download Reprint (PDF) | Download Errata (PDF)
 
22.  
Filament-directed intercellular contacts during differentiation of cultured chick myoblasts.
Singer RH, Pudney JA
Tissue Cell 16(1):17-29 (1984)
Abstract | Link to Journal | Download Reprint (PDF)
 
21.  
Analysis of receptor-ligand interactions using nitrocellulose gel transfer: application to Torpedo acetylcholine receptor and alpha-bungarotoxin.
Oblas B, Boyd ND, Singer RH
Anal Biochem 130(1):1-8 (1983 April 1)
Abstract | Link to Journal | Download Reprint (PDF)
 
20.  
Actin gene expression visualized in chicken muscle tissue culture by using in situ hybridization with a biotinated nucleotide analog.
Singer RH, Ward DC
Proc Natl Acad Sci U S A 79(23):7331-7335 (1982 December)
Abstract | Link to Journal | Download Reprint (PDF)
 
19.  
Increased turnover of proteins from the sarcoplasmic reticulum of dystrophic chicken muscle cells in tissue culture.
Ettienne EM, Swartz K, Singer RH
J Biol Chem 256(12):6408-6412 (1981 June 25)
Abstract | Link to Journal | Download Reprint (PDF)
 
18.  
Sea urchin tube feet: unique structures that allow a cytological and molecular approach to the study of actin and its gene expression.
Kabat-Zinn J, Singer RH
J Cell Biol 89(1):109-114 (1981 April)
Abstract | Link to Journal | Download Reprint (PDF)
 
17.  
Intracellular filament bundles in whole mounts of chick and human myoblasts extracted with triton X-100.
Pudney J, Singer RH
Tissue Cell 12(4):595-612 (1980)
Abstract | Link to Journal | Download Reprint (PDF)
 
16.  
Nerve Growth Factor Production by Muscle Cells.
Murphy R, Singer RH, Pantazis N, Saide J, Arnason B and Young M
In Muscle Regeneration, ed Mauro A, et al, 443. Raven Press: New York (1979)

 

 
15.  
Electron microscopic visualization of the filamentous reticulum in whole cultured presumptive chick myoblasts.
Pudney J, Singer RH
Am J Anat 156(3):321-336 (1979 November)
Abstract | Link to Journal | Download Reprint (PDF)
 
14.  
Ca2+ binding, ATP-dependent Ca2+ transport, and total tissue Ca2+ in embryonic and adult avian dystrophic pectoralis.
Ettienne EM, Singer RH
J Membr Biol 44(3-4):195-210 (1978 December 29)
Abstract | Link to Journal | Download Reprint (PDF)
 

13.

 
The capacity of polyadenylated RNA from myogenic cells treated with actinomycin D to direct protein synthesis in a cell-free system.
Kessler-Icekson G, Singer RH, Yaffe D
Eur J Biochem 88(2):403-410 (1978 August 1)
Abstract | Link to Journal | Download Reprint (PDF)
 
12.  
Stability of polyadenylated RNA in differentiating myogenic cells.
Singer RH, Kessler-Icekson G
Eur J Biochem 88(2):395-402 (1978 August 1)
Abstract | Link to Journal | Download Reprint (PDF)
 
11.  
Actin-containing microprocesses in the fusion of cultured chick myoblasts.
Huang HL, Singer RH, Lazarides E
Muscle Nerve 1(3):219-229 (1978 May)

Abstract | Link to Journal | Download Reprint (PDF)

 
10.  
Aberrant 35S Methionine Incorporation and Calcium Uptake into Dystrophic Pectoralis, Cardiac and Brain Membrane Vesicles.
Ettienne E, Singer R

In Calcium Binding Proteins and Calcium Function: Proceedings of the International Symposium on Calcium-Binding Proteins and Calcium Function in Health and Disease, June 5-9, 1977, ed Wasserman RH, et al, 491-495. Elsevier North-Holland (1977)

 

 
9.  
Synthesis and secretion of a high molecular weight form of nerve growth factor by skeletal muscle cells in culture.
Murphy RA, Singer RH, Saide JD, Pantazis NJ, Blanchard MH, Byron KS, Arnason BG, Young M
Proc Natl Acad Sci U S A 74(10):4496-4500 (1977 October)
Abstract | Link to Journal | Download Reprint (PDF)
 
8.  
Methods with insect cells in suspension culture. I. Aedes albopictus.
Spradling A, Singer RH, Lengyel J, Penman S
Methods Cell Biol 10:185-194 (1975)
 
 
7.  
The Relation of Protein Synthesis Regulation and mRNA Metabolism.
Penman S, Goldstein E, Reichman M, Singer RH
Karolinska Symposium 6:168 (1973)
 
 
6.  
The relation of protein synthesis regulation and RNA metabolism.
Penman S, Goldstein E, Reichman M, Singer R
Acta Endocrinol Suppl (Copenh)180:168-191 (1973)
 
 
5.  
Messenger RNA in HeLa cells: kinetics of formation and decay.
Singer RH, Penman S
J Mol Biol 78(2):321-334 (1973 August 5)
Abstract | Link to Journal | Download Reprint (PDF)
 
4.  
Stability of HeLa cell mRNA in actinomycin.
Singer RH, Penman S
Nature 240(5376):100-102 (1972 November 10)
Link to Journal | Download Reprint (PDF)
 
3.  
Transcription and Translation in Mammalian Cells.
Penman S, Price R, Perlman S, Singer RH
Proc Aust Biochem Soc 5:262 (1972)
Link to Journal
 
2.  
Analysis of limb morphogenesis in a model system.
Singer RH
Dev Biol 28(1):113-122 (1972 May)
Abstract | Link to Journal | Download Reprint (PDF)
 
1.  
The Photodynamic Action of Light on Hydra.
Singer RH, Rushforth N, Burnett A
J Exp Zool 154(2):169-173 (1963)
Abstract | Link to Journal | Download Reprint (PDF)
 
Other Publications Supported by Funding to the Singer Lab:
 
Structural and functional analysis of the costimulatory receptor programmed death-1.
Zhang X, Schwartz JC, Guo X, Bhatia S, Cao E, Lorenz M, Cammer M, Chen L, Zhang ZY, Edidin MA, Nathenson SG, Almo SC
Immunity 20(3):337-347(2004 March)
Abstract | Link to Journal | Download Reprint (PDF) | Download Errata (PDF)
 
 
Localization of trinucleotide repeat sequences in myotonic dystrophy cells using a single fluorochrome-labeled PNA probe.
Taneja KL
BioTechniques 24(3):472-476 (1998 March)
Abstract | Link to Journal | Download Reprint (PDF)
 
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